Gary J. Patti, PhD

Gary J. Patti, PhD

Primary Academic Title

Professor of Chemistry and of Genetics and Medicine, Michael and Tana Powell Professor of Chemistry, Washington University School of Medicine

Research Interest

We are interested in using advanced metabolic technologies to quantitatively cancer metabolism.


  • 2008: PhD, chemistry, Washington University, St. Louis


  • 2008 - 2011: NIH postdoctoral fellow, The Scripps Research Institute, La Jolla, Calif.

Selected Research Publications

Using mass spectrometry imaging to map fluxes quantitatively in the tumor ecosystem.
  • Schwaiger-Haber M, Stancliffe E, Anbukumar DS, [...] Patti GJ
  • Nat Commun 2023
Monounsaturated and Diunsaturated Fatty Acids Sensitize Cervical Cancer to Radiation Therapy.
  • Muhammad N, Ruiz F, Stanley J, [...] Patti GJ, Schwarz JK
  • Cancer Res 2022
Saturation of the mitochondrial NADH shuttles drives aerobic glycolysis in proliferating cells.
  • Wang Y, Stancliffe E, Fowle-Grider R, [...] Patti GJ
  • Mol Cell 2022
MYC sensitises cells to apoptosis by driving energetic demand.
  • Edwards-Hicks J, Su H, Mangolini M, [...] Patti GJ, [...] Finch AJ
  • Nat Commun 2022
A multidimensional metabolomics workflow to image biodistribution and evaluate pharmacodynamics in adult zebrafish.
  • Jackstadt MM, Chamberlain CA, Doonan SR, Shriver LP, Patti GJ
  • Dis Model Mech 2022
Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis.
  • Sletten AC, Davidson JW, Yagabasan B, [...] Patti GJ, [...] Schaffer JE
  • Nat Commun 2021
Isotope tracing in adult zebrafish reveals alanine cycling between melanoma and liver.
  • Naser FJ, Jackstadt MM, Fowle-Grider R, [...] Patti GJ
  • Cell Metab 2021
DecoID improves identification rates in metabolomics through database-assisted MS/MS deconvolution.
  • Stancliffe E, Schwaiger-Haber M, Sindelar M, Patti GJ
  • Nat Methods 2021

Contact Information

Contact Information