Sidharth V. Puram, MD, PhD

Sidharth V. Puram, MD, PhD


Primary Academic Title

Asssociate Professor of Otolaryngology, Division of Head and Neck Surgery, Washington University School of Medicine

Clinical Expertise

Head and neck surgery

Research Interest

Tumor heterogeneity in head and neck cancer and its implications for prognosis, treatment response, and underlying biology, head and neck squamous carcinoma, additional interests include salivary malignancies


  • 2013: MD, Harvard Medical School - MIT Health Sciences and Technology
  • 2011: PhD, pathology, Harvard Medical School


  • 2013 - 2014: Intern, general surgery, Massachusetts General Hospital, Boston
  • 2014 - 2017: Resident, otolaryngology, Harvard Combined Program in Otolaryngology
  • 2017 - 2018: Chief resident, otolaryngology, Harvard Combined Program in Otolaryngology
  • 2018 - 2019: Fellow, head and neck oncology, Ohio State University, Columbus

Board Certification

  • 2019: American Board of Otolaryngology (in review)

Selected Research Publications

Epigenetic regulation during cancer transitions across 11 tumour types.
  • Terekhanova NV, Karpova A, Liang WW, [...] Puram SV, [...] Ding L
  • Nature 2023
Changing Epidemiology of Oral Cavity Cancer in the United States.
  • Stepan KO, Mazul AL, Larson J, [...] Puram SV
  • Otolaryngol Head Neck Surg 2023
Epithelial-Mesenchymal Plasticity in Tumor Immune Evasion.
  • Mullins RDZ, Pal A, Barrett TF, Heft Neal ME, Puram SV
  • Cancer Res 2022
Partial EMT in head and neck cancer biology: a spectrum instead of a switch.
  • Pal A, Barrett TF, Paolini R, Parikh A, Puram SV
  • Oncogene 2021
The prognostic significance of race in nasopharyngeal carcinoma by histological subtype.
  • Stepan KO, Mazul AL, Skillington SA, [...] Puram SV
  • Head Neck 2021

View All Publications

Contact Information

  • Washington University Medical Campus

    4921 Parkview Place
    Saint Louis, MO 63110

Phone Numbers

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