Sidharth V. Puram, MD, PhD

Sidharth V. Puram, MD, PhD


Primary Academic Title

Associate Professor of Otolaryngology, Division of Head and Neck Surgery, Washington University School of Medicine

Clinical Expertise

Head and neck surgery

Research Interest

Tumor heterogeneity in head and neck cancer and its implications for prognosis, treatment response, and underlying biology, head and neck squamous carcinoma, additional interests include salivary malignancies


  • 2013: MD, Harvard Medical School - MIT Health Sciences and Technology
  • 2011: PhD, pathology, Harvard Medical School


  • 2013 - 2014: Intern, general surgery, Massachusetts General Hospital, Boston
  • 2014 - 2017: Resident, otolaryngology, Harvard Combined Program in Otolaryngology
  • 2017 - 2018: Chief resident, otolaryngology, Harvard Combined Program in Otolaryngology
  • 2018 - 2019: Fellow, head and neck oncology, Ohio State University, Columbus

Board Certification

  • 2019: American Board of Otolaryngology (in review)

Selected Research Publications

Patient Navigation for Timely, Guideline-Adherent Adjuvant Therapy for Head and Neck Cancer: A National Landscape Analysis.
  • Graboyes EM, Chappell M, Duckett KA, [...] Puram SV, [...] Calhoun E
  • J Natl Compr Canc Netw 2023
Epigenetic regulation during cancer transitions across 11 tumour types.
  • Terekhanova NV, Karpova A, Liang WW, [...] Puram SV, [...] Ding L
  • Nature 2023
Margins in Stage I and II Oral Cavity Squamous Cell Carcinoma: A Review From the American Head and Neck Society.
  • Puram SV, Mays AC, Bayon R, [...] Varvares MA
  • JAMA Otolaryngol Head Neck Surg 2023
Epigenetic regulation of hybrid epithelial-mesenchymal cell states in cancer.
  • Sample RA, Nogueira MF, Mitra RD, Puram SV
  • Oncogene 2023
Hallmarks of transcriptional intratumour heterogeneity across a thousand tumours.
  • Gavish A, Tyler M, Greenwald AC, [...] Puram SV, Tirosh I
  • Nature 2023
Changing Epidemiology of Oral Cavity Cancer in the United States.
  • Stepan KO, Mazul AL, Larson J, [...] Puram SV
  • Otolaryngol Head Neck Surg 2023

View All Publications

Contact Information

  • Washington University Medical Campus

    4921 Parkview Place
    Saint Louis, MO 63110

Phone Numbers

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