Sidharth V. Puram, MD, PhD

Sidharth V. Puram, MD, PhD

Surgeon

Primary Academic Title

Professor of Otolaryngology and Genetics, Chief, Division of Head and Neck Surgery, Director, Head and Neck Tumor Center, WashU Medicine

Clinical Expertise

Head and neck surgery

Research Interest

Tumor heterogeneity in head and neck cancer and its implications for prognosis, treatment response, and underlying biology, head and neck squamous carcinoma, additional interests include salivary malignancies

Education

  • 2013: MD, Harvard Medical School - MIT Health Sciences and Technology
  • 2011: PhD, pathology, Harvard Medical School

Training

  • 2013 - 2014: Intern, general surgery, Massachusetts General Hospital, Boston
  • 2014 - 2017: Resident, otolaryngology, Harvard Combined Program in Otolaryngology
  • 2017 - 2018: Chief resident, otolaryngology, Harvard Combined Program in Otolaryngology
  • 2018 - 2019: Fellow, head and neck oncology, Ohio State University, Columbus

Board Certification

  • 2019: American Board of Otolaryngology (in review)

Selected Research Publications

Immunotherapeutic strategies in head and neck cancer: challenges and opportunities.
  • Liu X, Harbison RA, Varvares MA, Puram SV , Peng G
  • J Clin Invest 2025
Use of Intraoperative Frozen Section to Assess Surgical Margins in HPV-Related Oropharyngeal Carcinoma.
  • Ramadan S, Bellas A, Al-Qurayshi Z, [...] Puram SV
  • JAMA Otolaryngol Head Neck Surg 2025
Tumour evolution and microenvironment interactions in 2D and 3D space.
  • Mo CK, Liu J, Chen S, [...] Puram SV, [...] Ding L
  • Nature 2024
Patient Navigation for Timely, Guideline-Adherent Adjuvant Therapy for Head and Neck Cancer: A National Landscape Analysis.
  • Graboyes EM, Chappell M, Duckett KA, [...] Puram SV, [...] Calhoun E
  • J Natl Compr Canc Netw 2023
Epigenetic regulation during cancer transitions across 11 tumour types.
  • Terekhanova NV, Karpova A, Liang WW, [...] Puram SV, [...] Ding L
  • Nature 2023

View All Publications

Contact Information

  • Gary C. Werths Building at Siteman Cancer Center

    4500 Forest Park Avenue
    Saint Louis, MO 63108

Phone Numbers

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