Kooresh Shoghi, PhD

Kooresh Shoghi, PhD

Primary Academic Title

Professor of Radiology, Washington University School of Medicine

Research Interest

Computational biology at the interface with molecular imaging. We have developed state-of-the-art image quantification and processing algorithms for quantification of PET images with applications to metabolism and cellular proliferation, among others. We use computational biology to facilitate the understanding of molecular imaging and therapeutic targets in health and disease.

Education

  • 2000: MS, biomathematics, University of California, Los Angeles
  • 2005: PhD, biomathematics, University of California

Selected Research Publications

Differential chromatin accessibility and transcriptional dynamics define breast cancer subtypes and their lineages.
  • Iglesia MD, Jayasinghe RG, Chen S, [...] Shoghi KI, [...] Ding L
  • Nat Cancer 2024
Tumour evolution and microenvironment interactions in 2D and 3D space.
  • Mo CK, Liu J, Chen S, [...] Shoghi KI, [...] Ding L
  • Nature 2024
Discovery and Targeting of a Noncanonical Mechanism of Sarcoma Resistance to ADI-PEG20 Mediated by the Microenvironment.
  • Rogers LC, Kremer JC, Brashears CB, [...] Shoghi KI, [...] Van Tine BA
  • Clin Cancer Res 2023
First-in-Humans Evaluation of Safety and Dosimetry of 64Cu-LLP2A for PET Imaging.
  • Laforest R, Ghai A, Fraum TJ, [...] Shoghi KI, [...] Dehdashti F
  • J Nucl Med 2023