Brian Van Tine, MD, PhD

Brian Van Tine, MD, PhD

Medical Oncologist

Primary Academic Title

Professor of medicine, Division of Oncology, Section of Medical Oncology, Washington University School of Medicine

Clinical Expertise

As a member of our sarcoma specialist team, Dr. Van Tine cares for patients diagnosed with sarcomas and rare tumors through treatment and recovery. Learn more about how Dr. Van Tine and Siteman approach extremity and non-extremity sarcoma treatment and recovery.

Research Interest

Clinical interest in the treatment of soft tissue and bone sarcomas. Research interest focuses on the study of the genomics and genetics of bone and soft tissue sarcomas. Using a combination of whole genomic sequencing and human in mouse xenografting, the Van Tine lab works to identify the druggable driving pathways for the treatment of sarcomas.

Education

  • 2003: PhD, HPV biology, University of Alabama, Birmingham
  • 2005: MD, University of Alabama

Training

  • 2005 - 2007: Intern and resident, internal medicine, Washington University, St. Louis
  • 2007 - 2011: Fellow, hematology and oncology, Washington University

Board Certification

  • 2009: Sarcoma

Selected Research Publications

High dimensional analyses reveal IL-15 enhances activation of Sipuleucel-T lymphocyte subsets and reverses immunoresistance.
  • Saeed MA, Peng B, Kim K, [...] Van Tine B, [...] Pachynski RK
  • Cancer Immunol Res 2024
Atezolizumab for Advanced Alveolar Soft Part Sarcoma.
  • Chen AP, Sharon E, O'Sullivan-Coyne G, [...] Van Tine BA, [...] Doroshow JH
  • N Engl J Med 2023
Nirogacestat, a γ-Secretase Inhibitor for Desmoid Tumors.
  • Gounder M, Ratan R, Alcindor T, [...] Van Tine BA, [...] Kasper B
  • N Engl J Med 2023
Relapsed Synovial Sarcoma: Treatment Options.
  • Weiss MC, Van Tine BA
  • Curr Treat Options Oncol 2023
Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness.
  • Li Y, Lih TM, Dhanasekaran SM, [...] Van Tine BA, [...] Ding L
  • Cancer Cell 2023
Olutasidenib (FT-2102) in patients with relapsed or refractory IDH1-mutant glioma: A multicenter, open-label, phase Ib/II trial.
  • de la Fuente MI, Colman H, Rosenthal M, Van Tine BA, [...] Monga V
  • Neuro-oncology 2023
Biomarker correlates with response to NY-ESO-1 TCR T cells in patients with synovial sarcoma.
  • Gyurdieva A, Zajic S, Chang YF, [...] Van Tine BA, [...] Eleftheriadou I
  • Nat Commun 2022

View All Publications

Contact Information

  • Washington University Medical Campus

    4921 Parkview Place
    Saint Louis, MO 63110

Phone Numbers

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