Ting Wang, PhD

Ting Wang, PhD

Primary Academic Title

Professor of Genetics, Washington University School of Medicine

Research Interest

Computational genomics and epigenomics. The evolution and adaption of human regulatory networks, with a focus on mobile elements (i.e., transposable elements) and their impact on gene regulation, their genetic and epigenetic control, and their roles in human biology and diseases. In particular, we are studying how DNA methylation changes in transposable elements influence tumorigenesis.

Education

  • 2001: MS, computer sciences, Washington University, St. Louis
  • 2006: PhD, computational biology, Washington University

Training

  • 2006 - 2009: Postdoctoral fellow, computational biology, University of California, Santa Cruz

Selected Research Publications

Exploring the epigenome profiles of repetitive elements with the WashU Repeat Browser.
  • Shen J, Cheng S, Purushotham D, [...] Wang T
  • Genome Res 2025
Regulatory transposable elements in the encyclopedia of DNA elements.
  • Du AY, Chobirko JD, Zhuo X, Feschotte C, Wang T
  • Nat Commun 2024
Cis-regulatory evolution of the recently expanded Ly49 gene family.
  • Fan C, Xing X, Murphy SJH, [...] Wang T
  • Nat Commun 2024
Towards targeting transposable elements for cancer therapy.
  • Liang Y, Qu X, Shah NM, Wang T
  • Nat Rev Cancer 2024
A distinct human cell type expressing MHCII and RORγt with dual characteristics of dendritic cells and type 3 innate lymphoid cells.
  • Ulezko Antonova A, Lonardi S, Monti M, [...] Wang T, [...] Colonna M
  • Proc Natl Acad Sci USA 2023
Modbed track: Visualization of modified bases in single-molecule sequencing.
  • Li D, Zhuo X, Harrison JK, Liu S, Wang T
  • Cell Genom 2023
Transposable elements in mammalian chromatin organization.
  • Lawson HA, Liang Y, Wang T
  • Nat Rev Genet 2023
Non-small Cell Lung Cancer Epigenomes Exhibit Altered DNA Methylation in Smokers and Never-smokers.
  • Karlow JA, Pehrsson EC, Xing X, [...] Wang T
  • Genomics Proteomics Bioinformatics 2023
A draft human pangenome reference.
  • Liao WW, Asri M, Ebler J, [...] Wang T, [...] Paten B
  • Nature 2023

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