Ting Wang, PhD

Ting Wang, PhD

Primary Academic Title

Professor of Genetics, Washington University School of Medicine

Research Interest

Computational genomics and epigenomics. The evolution and adaption of human regulatory networks, with a focus on mobile elements (i.e., transposable elements) and their impact on gene regulation, their genetic and epigenetic control, and their roles in human biology and diseases. In particular, we are studying how DNA methylation changes in transposable elements influence tumorigenesis.

Education

  • 2001: MS, computer sciences, Washington University, St. Louis
  • 2006: PhD, computational biology, Washington University

Training

  • 2006 - 2009: Postdoctoral fellow, computational biology, University of California, Santa Cruz

Selected Research Publications

Towards targeting transposable elements for cancer therapy.
  • Liang Y, Qu X, Shah NM, Wang T
  • Nat Rev Cancer 2024
A distinct human cell type expressing MHCII and RORγt with dual characteristics of dendritic cells and type 3 innate lymphoid cells.
  • Ulezko Antonova A, Lonardi S, Monti M, [...] Wang T, [...] Colonna M
  • Proc Natl Acad Sci USA 2023
Modbed track: Visualization of modified bases in single-molecule sequencing.
  • Li D, Zhuo X, Harrison JK, Liu S, Wang T
  • Cell Genom 2023
Transposable elements in mammalian chromatin organization.
  • Lawson HA, Liang Y, Wang T
  • Nat Rev Genet 2023
Non-small Cell Lung Cancer Epigenomes Exhibit Altered DNA Methylation in Smokers and Never-smokers.
  • Karlow JA, Pehrsson EC, Xing X, [...] Wang T
  • Genomics Proteomics Bioinformatics 2023
A draft human pangenome reference.
  • Liao WW, Asri M, Ebler J, [...] Wang T, [...] Paten B
  • Nature 2023
Widespread contribution of transposable elements to the rewiring of mammalian 3D genomes.
  • Choudhary MNK, Quaid K, Xing X, Schmidt H, Wang T
  • Nat Commun 2023
Semi-automated assembly of high-quality diploid human reference genomes.
  • Jarvis ED, Formenti G, Rhie A, [...] Wang T, [...] Miga KH
  • Nature 2022
The dynseq browser track shows context-specific features at nucleotide resolution.
  • Nair S, Barrett A, Li D, [...] Wang T, [...] Kundaje A
  • Nat Genet 2022

View All Publications