Lukas Wartman, MD

Lukas Wartman, MD

Bone Marrow Transplant Specialist, Medical Oncologist

Primary Academic Title

Assistant Professor of Medicine, Division of Oncology, Section of Stem Cell Biology, Washington University School of Medicine

Clinical Expertise

Hematologic malignancies, bone marrow transplant

Research Interest

Dr. Wartman led the study that sequenced the first mouse model of human cancer (a mouse model of leukemia developed in Dr. Timothy Ley's Laboratory). He recently started his own lab and is studying the role of loss of function mutations in Kdm6a, a histone H3K27 demethylase, in cancer pathogenesis. He also collaborates with investigators at The Genome Institute to organize a monthly Genomics Tumor Board.

Education

  • 2005: MD, Washington University, St. Louis

Training

  • 2005 - 2007: Resident, internal medicine, Washington University, St. Louis
  • 2007 - 2008: Clinical fellow, hematology and oncology, Washington University
  • 2008 - 2011: Research fellow, stem cell biology, Washington University

Selected Research Publications

Distinct clonal identities of B-ALLs arising after lenolidomide therapy for multiple myeloma.
  • Barnell EK, Skidmore ZL, Newcomer KF, [...] Wartman LD
  • Blood Adv 2023
Decitabine salvage for TP53-mutated, relapsed/refractory acute myeloid leukemia after cytotoxic induction therapy.
  • Ferraro F, Gruszczynska A, Ruzinova MB, [...] Wartman LD, [...] Welch JS
  • Haematologica 2022
Tumor suppressor function of WT1 in acute promyelocytic leukemia.
  • Christopher MJ, Katerndahl CDS, LeBlanc HR, [...] Wartman LD, [...] Ley TJ
  • Haematologica 2022
Immunosuppression and outcomes in adult patients with de novo acute myeloid leukemia with normal karyotypes.
  • Ferraro F, Miller CA, Christensen KA, [...] Wartman LD, [...] Ley TJ
  • Proc Natl Acad Sci USA 2021
Tumor suppressor function of Gata2 in acute promyelocytic leukemia.
  • Katerndahl CDS, Rogers ORS, Day RB, [...] Wartman LD, [...] Ley TJ
  • Blood 2021

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