The p53 protein requires communication between upstream activators in order to sense when a cell is under stress. One such activator is the ARF tumor supressor. These two proteins are among the most frequently affected genes in human cancer. We are interested in understanding the individual contribution of these proteins to the development of human cancers and how they may be regulated by upstream signals.
- 1997: PhD, cell and molecular biology, Saint Louis University
- 1997 - 2001: Postdoctoral associate, Howard Hughes Medical Institute, St. Jude Children's Research Hospital, Memphis, Tenn.
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