Jason Weber, PhD

Jason Weber, PhD

Primary Academic Title

Professor of Medicine, Division of Oncology, Section of Molecular Oncology, Washington University School of Medicine

Research Interest

The p53 protein requires communication between upstream activators in order to sense when a cell is under stress. One such activator is the ARF tumor supressor. These two proteins are among the most frequently affected genes in human cancer. We are interested in understanding the individual contribution of these proteins to the development of human cancers and how they may be regulated by upstream signals.

Education

  • 1997: PhD, cell and molecular biology, Saint Louis University

Training

  • 1997 - 2001: Postdoctoral associate, Howard Hughes Medical Institute, St. Jude Children's Research Hospital, Memphis, Tenn.

Selected Research Publications

Induction of Viral Mimicry Upon Loss of DHX9 and ADAR1 in Breast Cancer Cells.
  • Cottrell KA, Ryu S, Pierce JR, [...] Weber JD
  • Cancer Res Commun 2024
8-azaadenosine and 8-chloroadenosine are not selective inhibitors of ADAR.
  • Cottrell KA, Torres LS, Dizon MG, Weber JD
  • Cancer Res Commun 2021

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