William Chapman, MD, FACS

William Chapman, MD, FACS


Primary Academic Title

Eugene M. Bricker Chair of Surgery and Chief, Division of General Surgery and Section of Transplant Surgery, Washington University School of Medicine

Clinical Expertise

As chief of the Section of Transplant Surgery and chief of the Division of General Surgery, Dr. Chapman is committed to providing patients with exceptional liver cancer care. Learn more about how Dr. Chapman and our liver cancer speclialist team approach diagnosis and staging, treatment and recovery.

Research Interest

1) Image-guided liver surgery: Development and application of techniques for image guidance in resectional ablative liver surgery. 2) Multisystem inflammation following hapatic injury: This project investigates consequences of hepatic injury and response to direct liver injury. 3) Enhanced treatment of hepatocellular carcinoma.


  • 1984: MD, Medical University of South Carolina, Charleston


  • 1984 - 1987: Resident, surgery, Vanderbilt University, Nashville, Tenn.
  • 1987 - 1989: Research fellow, hepatobiliary disease, Vanderbilt University
  • 1990 - 1991: Chief resident,general surgery, Vanderbilt University
  • 1991 - 1992: Fellow, hepatobiliary surgery and liver transplantation, Kings College Hospital, London

Board Certification

  • 2001: American Board of Surgery, Surgery
  • 2001: American Board of Surgery, Surgical Critical Care

Selected Research Publications

Transplantation for Hepatocellular Carcinoma.
  • Hill A, Olumba F, Chapman W
  • Surg Clin North Am 2024
Integrated analysis of genomic and transcriptomic data for the discovery of splice-associated variants in cancer.
  • Cotto KC, Feng YY, Ramu A, [...] Chapman WC, [...] Griffith M
  • Nat Commun 2023
Ten-Year Outcomes of Liver Transplant and Downstaging for Hepatocellular Carcinoma.
  • Tabrizian P, Holzner ML, Mehta N, [...] Chapman WC, [...] Llovet JM
  • JAMA Surg 2022
Enucleation of Biliary Cystadenomas: a Review.
  • Strasberg SM, Chapman WC
  • J Gastrointest Surg 2021

Contact Information

  • Washington University Medical Campus

    4921 Parkview Place
    Saint Louis, MO 63110

  • West St. Louis County

    Medical Office Building 2, 10 Barnes West Drive
    Creve Coeur, MO 63141

Phone Numbers

Request an appointment