selective serotonin reuptake inhibitor

Definition of selective serotonin reuptake inhibitor

selective serotonin reuptake inhibitor

(seh-LEK-tiv SAYR-uh-TOH-nin ree-UP-tayk in-HIH-bih-ter)
A type of drug that is used to treat depression and some other conditions. Selective serotonin reuptake inhibitors stop or delay the body from reabsorbing a substance called serotonin, which leaves more of it available for the body to use. Raising serotonin levels can help regulate mood, appetite, digestion, sleep, and many other bodily functions. Selective serotonin reuptake inhibitors include drugs such as citalopram, escitalopram, fluoxetine, paroxetine, and sertraline. Also called SSRI.

Source: NCI Dictionary of Cancer Terms