multiplex ligation-dependent probe amplification

Definition of multiplex ligation-dependent probe amplification

multiplex ligation-dependent probe amplification

(MUL-tee-plex ly-GAY-shun-deh-PEN-dent probe AM-plih-fih-KAY-shun)
A laboratory method commonly used for the detection of unusual copy number changes (insertions or deletions) of genomic sequences. Also called MLPA.

Source: NCI Dictionary of Cancer Terms