X-linked dominant

Definition of X-linked dominant inheritance

X-linked dominant inheritance (... linkt DAH-mih-nunt in-HAYR-ih-tunts): One of the ways a genetic trait or condition caused by a mutated (changed) gene on the X chromosome can be passed down (inherited) from parent to child. In X-linked dominant inheritance, a genetic condition can occur when the child inherits one copy of a mutated (changed) gene on the X chromosome from one parent. Daughters have a 50% chance of inheriting the mutated X-linked gene from their mother and a 100% chance of inheriting the mutated X-linked gene from their father. Sons have a 50% chance of inheriting the mutated X-linked gene from their mother and a 0% chance of inheriting the mutated X-linked gene from their father.

Source: NCI Dictionary of Cancer Terms

X-linked dominant inheritance