mogamulizumab

Definition of mogamulizumab

mogamulizumab (moh-GAM-yoo-LIH-zoo-mab): A drug used to treat adults with mycosis fungoides or Sezary syndrome (types of cutaneous T-cell lymphoma) that came back or did not get better after treatment with at least one systemic therapy. It is also being studied in the treatment of other types of cancer. Mogamulizumab binds to a protein called CCR4, which is found on some T cells (a type of white blood cell) and some types of lymphoma cells. Mogamulizumab may block this protein and help the immune system kill cancer cells. It is a type of monoclonal antibody. Also called Poteligeo.

Source: NCI Dictionary of Cancer Terms