cascade testing

Definition of cascade testing

cascade testing (kas-KADE TES-ting): The process of extending genetic testing to individuals at risk within a family for inheriting a pathogenic variant previously identified in a biologic relative. This process is repeated as more pathogenic variant carriers are identified within the family. Cascade testing is sometimes referred to as cascade screening, although cascade testing is the preferred term. Also called cascade genetic testing.

Source: NCI Dictionary of Cancer Terms