sacituzumab govitecan

Definition of sacituzumab govitecan

sacituzumab govitecan

(SAK-ih-TOO-zoo-mab GOH-vih-TEE-kan)
A drug used to treat adults with certain types of urothelial cancer (a type of cancer in the bladder or urinary tract) or breast cancer that have already been treated with other therapy. It is also being studied in the treatment of other types of cancer. Sacituzumab govitecan contains a monoclonal antibody called sacituzumab that binds to a protein called TROP2, which is found on some cancer cells. It also contains an anticancer drug called SN-38, which may help kill cancer cells. Sacituzumab govitecan is a type of antibody-drug conjugate. Also called Trodelvy.

Source: NCI Dictionary of Cancer Terms