Li  Ding, PhD

Li Ding, PhD

Primary Academic Title

Professor of Medicine, Division of Oncology, Section of Stem Cell Biology, Washington University School of Medicine

Research Interest

Identifying and characterizing somatic/germline genetic changes relevant to cancer initiation and progression as well as drug response by integrating various data types, including DNA, RNA and proteomics data. Developing algorithms to facilitate the translation of genomic findings to clinical practice.

Education

  • 1998: PhD, biochemistry, University of Utah, Salt Lake City

Training

  • 1998 - 2999: Postdoctoral fellow, biochemistry, Stanford University, Palo Alto, Calif.

Selected Research Publications

Senescence Defines a Distinct Subset of Myofibroblasts That Orchestrates Immunosuppression in Pancreatic Cancer.
  • Belle JI, Sen D, Baer JM, [...] Ding L, [...] DeNardo DG
  • Cancer Discov 2024
SenNet recommendations for detecting senescent cells in different tissues.
  • Suryadevara V, Hudgins AD, Rajesh A, [...] Ding L, [...] Neretti N
  • Nat Rev Mol Cell Biol 2024
Comprehensive proteogenomic characterization of rare kidney tumors.
  • Li GX, Chen L, Hsiao Y, [...] Ding L, [...] Nesvizhskii AI
  • Cell Rep Med 2024
Single-nucleotide variant calling in single-cell sequencing data with Monopogen.
  • Dou J, Tan Y, Kock KH, [...] Ding L, [...] Chen K
  • Nat Biotechnol 2024
Senescence Defines a Distinct Subset of Myofibroblasts That Orchestrates Immunosuppression in Pancreatic Cancer.
  • Belle JI, Sen D, Baer JM, [...] Ding L, [...] DeNardo DG
  • Cancer Discov 2024
Epigenetic regulation during cancer transitions across 11 tumour types.
  • Terekhanova NV, Karpova A, Liang WW, [...] Ding L
  • Nature 2023
Deep learning integrates histopathology and proteogenomics at a pan-cancer level.
  • Wang JM, Hong R, Demicco EG, [...] Ding L, [...] Fenyö D
  • Cell Rep Med 2023
Fibrosis induced by resident macrophages has divergent roles in pancreas inflammatory injury and PDAC.
  • Baer JM, Zuo C, Kang LI, [...] Ding L, [...] DeNardo DG
  • Nat Immunol 2023
Pan-cancer proteogenomics connects oncogenic drivers to functional states.
  • Li Y, Porta-Pardo E, Tokheim C, [...] Ding L
  • Cell 2023

View All Publications