John DiPersio, MD, PhD

John DiPersio, MD, PhD

Bone Marrow Transplant Specialist, Medical Oncologist

Primary Academic Title

Virginia E. and Sam J. Golman Endowed Professor in Medicine; Chief, Division of Oncology; Director, Center for Gene and Cellular Immunotherapy; Professor of Medicine, Pathology & Immunology, Washington University School of Medicine

Clinical Expertise

Bone marrow transplantation and leukemia

Research Interest

Molecular biology of cytokine receptor signaling; use and manipulation of mobilized peripheral blood stem cells for autologous and allogeneic transplantation; genetic manipulation of T cells using suicide genes; and targeted gene expression in early hematopoietic stem cells.


  • 1980: MD/PhD, microbiology, University of Rochester, Rochester, N.Y.


  • 1980 - 1984: Intern and resident, internal medicine, University of Texas Southwestern Medical Center, Dallas
  • 1984 - 1987: Fellow, hematology/oncology, University of California, Los Angeles

Board Certification

  • 1984: American Board of Internal Medicine, Internal Medicine
  • 1987: American Board of Internal Medicine, Medical Oncology
  • 1988: American Board of Internal Medicine, Hematology

Selected Research Publications

First-in-Humans Evaluation of Safety and Dosimetry of 64Cu-LLP2A for PET Imaging.
  • Laforest R, Ghai A, Fraum TJ, [...] DiPersio JF, [...] Dehdashti F
  • J Nucl Med 2023
The role of allogeneic transplant for adult Ph+ ALL in CR1 with complete molecular remission: a retrospective analysis.
  • Ghobadi A, Slade M, Kantarjian H, [...] DiPersio JF, [...] Kebriaei P
  • Blood 2022
Ponatinib after failure of second-generation tyrosine kinase inhibitor in resistant chronic-phase chronic myeloid leukemia.
  • Kantarjian HM, Jabbour E, Deininger M, [...] DiPersio J, [...] Mauro M
  • Am J Hematol 2022
Proteomic and phosphoproteomic landscapes of acute myeloid leukemia.
  • Kramer MH, Zhang Q, Sprung R, [...] DiPersio JF, [...] Ley TJ
  • Blood 2022
Decitabine salvage for TP53-mutated, relapsed/refractory acute myeloid leukemia after cytotoxic induction therapy.
  • Ferraro F, Gruszczynska A, Ruzinova MB, [...] DiPersio JF, [...] Welch JS
  • Haematologica 2022
Focal disruption of DNA methylation dynamics at enhancers in IDH-mutant AML cells.
  • Wilson ER, Helton NM, Heath SE, [...] DiPersio JF, [...] Spencer DH
  • Leukemia 2022
Systemic IL-15 promotes allogeneic cell rejection in patients treated with natural killer cell adoptive therapy.
  • Berrien-Elliott MM, Becker-Hapak M, Cashen AF, [...] DiPersio JF, [...] Fehniger TA
  • Blood 2022
Hematopoietic cell transplantation donor-derived memory-like NK cells functionally persist after transfer into patients with leukemia.
  • Berrien-Elliott MM, Foltz JA, Russler-Germain DA, [...] DiPersio JF, [...] Fehniger TA
  • Sci Transl Med 2022

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Contact Information

  • Washington University Medical Campus

    4921 Parkview Place
    Saint Louis, MO 63110

Phone Numbers

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