John DiPersio, MD, PhD

John DiPersio, MD, PhD

Bone Marrow Transplant Specialist, Medical Oncologist

Primary Academic Title

Virginia E. and Sam J. Golman Endowed Professorship of Medicine, Pathology & Immunology; Professor of Pediatrics; Director, Center for Gene and Cellular Immunotherapy, Washington University School of Medicine

Clinical Expertise

Bone marrow transplantation and leukemia

Research Interest

Molecular biology of cytokine receptor signaling; use and manipulation of mobilized peripheral blood stem cells for autologous and allogeneic transplantation; genetic manipulation of T cells using suicide genes; and targeted gene expression in early hematopoietic stem cells.


  • 1980: MD/PhD, microbiology, University of Rochester, Rochester, N.Y.


  • 1980 - 1984: Intern and resident, internal medicine, University of Texas Southwestern Medical Center, Dallas
  • 1984 - 1987: Fellow, hematology/oncology, University of California, Los Angeles

Board Certification

  • 1984: American Board of Internal Medicine, Internal Medicine
  • 1987: American Board of Internal Medicine, Medical Oncology
  • 1988: American Board of Internal Medicine, Hematology

Selected Research Publications

Targeting CXCR4, VLA-4, and CXCR2 for hematopoietic stem cell mobilization.
  • Cancilla D, Rettig MP, Karpova D, [...] DiPersio JF
  • Blood Adv 2024
An "off-the-shelf" CD2 universal CAR-T therapy for T-cell malignancies.
  • Xiang J, Devenport JM, Carter AJ, [...] DiPersio JF
  • Leukemia 2023
Epigenetic regulation during cancer transitions across 11 tumour types.
  • Terekhanova NV, Karpova A, Liang WW, [...] DiPersio JF, [...] Ding L
  • Nature 2023
Anti-myeloma efficacy of CAR-iNKT is enhanced with a long-acting IL-7, rhIL-7-hyFc.
  • O'Neal J, Cooper ML, Ritchey JK, [...] DiPersio JF
  • Blood Adv 2023
The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia.
  • Issa GC, Aldoss I, DiPersio J, [...] Stein EM
  • Nature 2023
First-in-Humans Evaluation of Safety and Dosimetry of 64Cu-LLP2A for PET Imaging.
  • Laforest R, Ghai A, Fraum TJ, [...] DiPersio JF, [...] Dehdashti F
  • J Nucl Med 2023
The role of allogeneic transplant for adult Ph+ ALL in CR1 with complete molecular remission: a retrospective analysis.
  • Ghobadi A, Slade M, Kantarjian H, [...] DiPersio JF, [...] Kebriaei P
  • Blood 2022
Ponatinib after failure of second-generation tyrosine kinase inhibitor in resistant chronic-phase chronic myeloid leukemia.
  • Kantarjian HM, Jabbour E, Deininger M, [...] DiPersio J, [...] Mauro M
  • Am J Hematol 2022

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Contact Information

  • Washington University Medical Campus

    4921 Parkview Place
    Saint Louis, MO 63110

Phone Numbers

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