John DiPersio, MD, PhD

John DiPersio, MD, PhD

Bone Marrow Transplant Specialist, Medical Oncologist

Primary Academic Title

Virginia E. and Sam J. Golman Endowed Professorship of Medicine, Pathology & Immunology; Professor of Pediatrics; Director, Center for Gene and Cellular Immunotherapy, Washington University School of Medicine

Clinical Expertise

Bone marrow transplantation and leukemia

Research Interest

Molecular biology of cytokine receptor signaling; use and manipulation of mobilized peripheral blood stem cells for autologous and allogeneic transplantation; genetic manipulation of T cells using suicide genes; and targeted gene expression in early hematopoietic stem cells.

Education

  • 1980: MD/PhD, microbiology, University of Rochester, Rochester, N.Y.

Training

  • 1980 - 1984: Intern and resident, internal medicine, University of Texas Southwestern Medical Center, Dallas
  • 1984 - 1987: Fellow, hematology/oncology, University of California, Los Angeles

Board Certification

  • 1984: American Board of Internal Medicine, Internal Medicine
  • 1987: American Board of Internal Medicine, Medical Oncology
  • 1988: American Board of Internal Medicine, Hematology

Selected Research Publications

Menin Inhibition With Revumenib for KMT2A-Rearranged Relapsed or Refractory Acute Leukemia (AUGMENT-101).
  • Issa GC, Aldoss I, Thirman MJ, DiPersio J, [...] Stein EM
  • J Clin Oncol 2025
Monitoring clonal burden as an alternative to blast count for myelodysplastic neoplasm treatment response.
  • Jacoby MA, Duncavage ED, Khanna A, [...] DiPersio JF, [...] Walter MJ
  • Leukemia 2025
Rational Protein Engineering to Enhance MHC-Independent T-cell Receptors.
  • Chang JF, Landmann JH, Chang TC, [...] DiPersio JF, [...] Singh N
  • Cancer Discov 2024
Phase 1 study of CAR-37 T cells in patients with relapsed or refractory CD37+ lymphoid malignancies.
  • Frigault MJ, Graham CE, Berger TR, [...] DiPersio JF, [...] Maus MV
  • Blood 2024
Targeting CXCR4, VLA-4, and CXCR2 for hematopoietic stem cell mobilization.
  • Cancilla D, Rettig MP, Karpova D, [...] DiPersio JF
  • Blood Adv 2024
Traversing the bench to bedside journey for iNKT cell therapies.
  • O'Neal J, Mavers M, Jayasinghe RG, DiPersio JF
  • Front Immunol 2024
An "off-the-shelf" CD2 universal CAR-T therapy for T-cell malignancies.
  • Xiang J, Devenport JM, Carter AJ, [...] DiPersio JF
  • Leukemia 2023

View All Publications

Contact Information

  • Washington University Medical Campus

    4500 Forest Park Avenue
    Saint Louis, MO 63108

Phone Numbers

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