John DiPersio, MD, PhD

John DiPersio, MD, PhD

Bone Marrow Transplant Specialist, Medical Oncologist

Primary Academic Title

Virginia E. and Sam J. Golman Endowed Professorship of Medicine, Pathology & Immunology; Professor of Pediatrics; Director, Center for Gene and Cellular Immunotherapy, WashU Medicine

Clinical Expertise

Bone marrow transplantation and leukemia

Research Interest

Molecular biology of cytokine receptor signaling; use and manipulation of mobilized peripheral blood stem cells for autologous and allogeneic transplantation; genetic manipulation of T cells using suicide genes; and targeted gene expression in early hematopoietic stem cells.

Education

  • 1980: MD/PhD, microbiology, University of Rochester, Rochester, N.Y.

Training

  • 1980 - 1984: Intern and resident, internal medicine, University of Texas Southwestern Medical Center, Dallas
  • 1984 - 1987: Fellow, hematology/oncology, University of California, Los Angeles

Board Certification

  • 1984: American Board of Internal Medicine, Internal Medicine
  • 1987: American Board of Internal Medicine, Medical Oncology
  • 1988: American Board of Internal Medicine, Hematology

Selected Research Publications

Clonal Hematopoiesis Landscape in Frequent Blood Donors.
  • Karpova D, Huerga Encabo H, Donato E, [...] DiPersio JF, [...] Trumpp A
  • Blood 2025
Treatment of non-Hodgkin lymphoma with point-of-care manufactured CAR T cells: a dual institution, phase 1 trial.
  • Ghobadi A, Caimi PF, Reese JS, [...] DiPersio J, [...] de Lima M
  • EClinicalMedicine 2025
Menin Inhibition With Revumenib for KMT2A-Rearranged Relapsed or Refractory Acute Leukemia (AUGMENT-101).
  • Issa GC, Aldoss I, Thirman MJ, DiPersio J, [...] Stein EM
  • J Clin Oncol 2025
Monitoring clonal burden as an alternative to blast count for myelodysplastic neoplasm treatment response.
  • Jacoby MA, Duncavage ED, Khanna A, [...] DiPersio JF, [...] Walter MJ
  • Leukemia 2025
Rational Protein Engineering to Enhance MHC-Independent T-cell Receptors.
  • Chang JF, Landmann JH, Chang TC, [...] DiPersio JF, [...] Singh N
  • Cancer Discov 2024
Phase 1 study of CAR-37 T cells in patients with relapsed or refractory CD37+ lymphoid malignancies.
  • Frigault MJ, Graham CE, Berger TR, [...] DiPersio JF, [...] Maus MV
  • Blood 2024
Targeting CXCR4, VLA-4, and CXCR2 for hematopoietic stem cell mobilization.
  • Cancilla D, Rettig MP, Karpova D, [...] DiPersio JF
  • Blood Adv 2024

View All Publications

Contact Information

  • Washington University Medical Campus

    Gary C. Werths Building at Siteman Cancer Center
    4500 Forest Park Avenue
    Saint Louis, MO 63108

    Center for Advanced Medicine at Siteman Cancer Center
    4921 Parkview Place
    Saint Louis, MO 63110

    Parkview Tower
    1 Parkview Place
    Saint Louis, MO 63110

    S. Lee Kling Proton Therapy Center
    224 Euclid Ave.
    Saint Louis, MO 63110

    Siteman Kids at St. Louis Children’s Hospital
    1 Children's Place
    St. Louis, MO 63110

Phone Numbers

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