Christopher Maher, PhD

Christopher Maher, PhD

Primary Academic Title

Professor of Medicine, Division of Oncology, Section of Molecular Oncology, Washington University School of Medicine

Research Interest

Translating genome-based knowledge through integrative analysis of high-throughput genomic technologies into the development of novel diagnostic, prognostic and therapeutic strategies in cancer. Developing novel computational approaches to elucidate “driver” mutations within common carcinomas that may be hidden by nonspecific aberrations that will subsequently be validated in preclinical models.


  • 2004: MS, biomedical engineering, Stony Brook University/Cold Spring Harbor Laboratory, Stony Brook, N.Y.
  • 2006: PhD, biomedical engineering, Stony Brook University/Cold Spring Harbor Laboratory


  • 2007 - : Postdoctoral fellow, cancer genomics, University of Western Cape, Cape Town, South Africa
  • 2007 - 2009: Postdoctoral fellow, cancer genomics, University of Michigan, Ann Arbor

Selected Research Publications

PACT: a pipeline for analysis of circulating tumor DNA.
  • Webster J, Dang HX, Chauhan PS, [...] Maher CA
  • Bioinformatics 2023
The 5-Hydroxymethylcytosine Landscape of Prostate Cancer.
  • Sjöström M, Zhao SG, Levy S, [...] Maher CA, [...] Feng FY
  • Cancer Res 2022
DANSR: A Tool for the Detection of Annotated and Novel Small RNAs.
  • Zhang J, Eteleeb AM, Rozycki EB, [...] Maher CA
  • Noncoding RNA 2022
Loss of Long Noncoding RNA NXTAR in Prostate Cancer Augments Androgen Receptor Expression and Enzalutamide Resistance.
  • Ghildiyal R, Sawant M, Renganathan A, [...] Maher CA, [...] Mahajan NP
  • Cancer Res 2022
Phase 1 study combining alisertib with nab-paclitaxel in patients with advanced solid malignancies.
  • Lim KH, Opyrchal M, Acharya A, [...] Maher CA, Wang-Gillam A
  • Eur J Cancer 2021
Long noncoding RNAs in cancer metastasis.
  • Liu SJ, Dang HX, Lim DA, Feng FY, Maher CA
  • Nat Rev Cancer 2021

View All Publications