Gabriel Mbalaviele, PhD

Primary Academic Title

Professor of Medicine, Division of Bone and Mineral Diseases, Washington University School of Medicine

Research Interest

Role of inflammasomes and gasdermins in pathophysiology.

Education

1992: PhD, University of Paris 7

Training

2007 - 2010: Associate research fellow, St. Louis, Mo.

Selected Research Publications

Tmem178 Negatively Regulates IL-1β Production Through Inhibition of the NLRP3 Inflammasome.

Khanna K, Yan H, Mehra M, [...] Mbalaviele G, [...] Faccio R
Arthritis Rheumatol 2024

IL-1β expression in bone marrow dendritic cells is induced by TLR2 agonists and regulates HSC function.

Li S, Yao JC, Oetjen KA, [...] Mbalaviele G, [...] Link DC
Blood 2022

Compound loss of GSDMD and GSDME function is necessary to achieve maximal therapeutic effect in colitis.

Xiao J, Sun K, Wang C, Abu-Amer Y, Mbalaviele G
J Transl Autoimmun 2022

Inhibition of the NLRP3 inflammasome improves lifespan in animal murine model of Hutchinson-Gilford Progeria.

González-Dominguez A, Montañez R, Castejón-Vega B, [...] Mbalaviele G, [...] Cordero MD
EMBO Mol Med 2021

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