Christopher Miller, PhD

Christopher Miller, PhD

Primary Academic Title

Assistant Professor of Medicine, Division of Oncology, Washington University School of Medicine

Research Interest

Developing and applying genomic and bioinformatic technologies to understand the origins of cancer


  • 2011: PhD, structural and computational biology and molecular biophysics program, Baylor College of Medicine, Houston

Selected Research Publications

Computational prediction of MHC anchor locations guides neoantigen identification and prioritization.
  • Xia H, McMichael J, Becker-Hapak M, [...] Miller CA, [...] Griffith M
  • Sci Immunol 2023
Clonal Hematopoiesis and Risk of Incident Lung Cancer.
  • Tian R, Wiley B, Liu J, [...] Miller CA, [...] Cao Y
  • J Clin Oncol 2023
Proteomic and phosphoproteomic landscapes of acute myeloid leukemia.
  • Kramer MH, Zhang Q, Sprung R, [...] Miller CA, [...] Ley TJ
  • Blood 2022
Decitabine salvage for TP53-mutated, relapsed/refractory acute myeloid leukemia after cytotoxic induction therapy.
  • Ferraro F, Gruszczynska A, Ruzinova MB, Miller CA, [...] Welch JS
  • Haematologica 2022
Focal disruption of DNA methylation dynamics at enhancers in IDH-mutant AML cells.
  • Wilson ER, Helton NM, Heath SE, [...] Miller CA, [...] Spencer DH
  • Leukemia 2022
Failure to Detect Mutations in U2AF1 due to Changes in the GRCh38 Reference Sequence.
  • Miller CA, Walker JR, Jensen TL, [...] Walter MJ
  • J Mol Diagn 2022
Tumor suppressor function of WT1 in acute promyelocytic leukemia.
  • Christopher MJ, Katerndahl CDS, LeBlanc HR, [...] Miller CA, Ley TJ
  • Haematologica 2022
Immunosuppression and outcomes in adult patients with de novo acute myeloid leukemia with normal karyotypes.
  • Ferraro F, Miller CA, Christensen KA, [...] Ley TJ
  • Proc Natl Acad Sci USA 2021
U2af1 is a haplo-essential gene required for hematopoietic cancer cell survival in mice.
  • Wadugu BA, Nonavinkere Srivatsan S, Heard A, [...] Miller CA, [...] Walter MJ
  • J Clin Invest 2021
Tumor suppressor function of Gata2 in acute promyelocytic leukemia.
  • Katerndahl CDS, Rogers ORS, Day RB, [...] Miller CA, Ley TJ
  • Blood 2021
Functional and epigenetic phenotypes of humans and mice with DNMT3A Overgrowth Syndrome.
  • Smith AM, LaValle TA, Shinawi M, [...] Miller CA, Ley TJ
  • Nat Commun 2021

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