Russell Pachynski, MD

Russell Pachynski, MD

Medical Oncologist

Primary Academic Title

Associate Professor of Medicine, Division of Medical Oncology, Director of GU Oncology Research, Washington University School of Medicine

Clinical Expertise

As a member of our kidney, bladder and prostate cancer specialist teams, Dr. Pachynski cares for patients diagnosed with these cancers through treatment and recovery.

Research Interest

My clinical specialty is genitourinary cancers, with a focus on prostate cancer. I also maintain an active lab focusing on leukocyte trafficking and its role in tumor immunology, with the ultimate goal of advantageously controlling this for patients’ benefits. I hope to advance translational immunotherapy and be able to bring novel therapies from the bench to the bedside, and back again.


  • 2003: MD, University of Wisconsin-Madison Medical School


  • 2003 - 2006: Resident, internal medicine, Stanford University Medical Center, Stanford, Calif.
  • 2006 - 2010: Fellow, oncology, Stanford University

Board Certification

  • 2007: American Board of Internal Medicine
  • 2017: American Board of Internal Medicine- medical oncology

Selected Research Publications

Beyond Average: α-Particle Distribution and Dose Heterogeneity in Bone Metastatic Prostate Cancer.
  • Benabdallah N, Lu P, Abou DS, [...] Pachynski RK, Thorek DLJ
  • J Nucl Med 2024
Epigenetic regulation during cancer transitions across 11 tumour types.
  • Terekhanova NV, Karpova A, Liang WW, [...] Pachynski R, [...] Ding L
  • Nature 2023
Prostate cancer immunotherapy: Improving clinical outcomes with a multi-pronged approach.
  • Sridaran D, Bradshaw E, DeSelm C, Pachynski R, [...] Mahajan NP
  • Cell Rep Med 2023
Chemerin triggers migration of a CD8 T cell subset with natural killer cell functions.
  • Ballet R, LaJevic M, Huskey-Mullin N, [...] Pachynski RK, [...] Zabel BA
  • Mol Ther 2023
Preservation of Proteins in Human Plasma through Metal-Organic Framework Encapsulation.
  • Wang Y, Morrissey JJ, Gupta P, [...] Pachynski RK, [...] Singamaneni S
  • ACS Appl Mater Interfaces 2023
IMC-Denoise: a content aware denoising pipeline to enhance Imaging Mass Cytometry.
  • Lu P, Oetjen KA, Bender DE, [...] Pachynski RK, [...] Thorek DLJ
  • Nat Commun 2023
Histopathologic and proteogenomic heterogeneity reveals features of clear cell renal cell carcinoma aggressiveness.
  • Li Y, Lih TM, Dhanasekaran SM, [...] Pachynski R, [...] Ding L
  • Cancer Cell 2023
Blind Image Restoration Enhances Digital Autoradiographic Imaging of Radiopharmaceutical Tissue Distribution.
  • Peng L, Nadia B, Wen J, [...] Pachynski RK, [...] Thorek DL
  • J Nucl Med 2022
Videos of Sipuleucel-T Programmed T Cells Lysing Cells That Express Prostate Cancer Target Antigens.
  • Kibel AS, Inman BA, Pachynski RK, [...] Petrylak DP
  • J Natl Cancer Inst 2022

Contact Information

  • West St. Louis County

    Medical Office Building 2, 10 Barnes West Drive
    Creve Coeur, MO 63141

  • Washington University Medical Campus

    4921 Parkview Place
    Saint Louis, MO 63110

Phone Numbers

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