Robert Schreiber, PhD

Robert Schreiber, PhD

Primary Academic Title

Andrew M. and Jane M. Bursky Distinguished Professor of Immunobiology, Washington University School of Medicine

Research Interest

Biology and signaling of cytokines with special emphasis on IFN-gamma and TNF; role of IFN-gamma in tumor immunity.


  • 1973: PhD, biochemistry and immunology, State University of New York, Buffalo


  • 1973 - : Postdoctoral fellow, medicine and biochemistry, State University of New York, Buffalo
  • 1973 - 1976: Postdoctoral fellow, molecular immunology, Scripps Research Institute, La Jolla, Calif

Selected Research Publications

TREM2 deficiency reprograms intestinal macrophages and microbiota to enhance anti-PD-1 tumor immunotherapy.
  • Di Luccia B, Molgora M, Khantakova D, [...] Schreiber RD, [...] Colonna M
  • Sci Immunol 2024
IL-2 targeted to CD8+ T cells promotes robust effector T cell responses and potent antitumor immunity.
  • Moynihan KD, Kumar MP, Sultan H, [...] Schreiber RD, [...] Djuretic IM
  • Cancer Discov 2024
CD5 expression by dendritic cells directs T cell immunity and sustains immunotherapy responses.
  • He M, Roussak K, Ma F, [...] Schreiber RD, [...] Klechevsky E
  • Science 2023
Cancer Immunology Research: A Decade of Illumination and Innovation.
  • Schreiber RD, Greenberg PD
  • Cancer Immunol Res 2023
Mechanisms of CD40-dependent cDC1 licensing beyond costimulation.
  • Wu R, Ohara RA, Jo S, [...] Schreiber RD, [...] Murphy KM
  • Nat Immunol 2022
Radiation-induced neoantigens broaden the immunotherapeutic window of cancers with low mutational loads.
  • Lussier DM, Alspach E, Ward JP, [...] Schreiber RD
  • Proc Natl Acad Sci USA 2021

View All Publications