avelumab

Pronunciation: (a-VEL-yoo-mab)

A drug used to treat urothelial carcinoma (a type of bladder cancer) that has advanced or spread to other parts of the body. It is used in patients whose disease got worse during or after treatment with anticancer drugs that included platinum. Avelumab is also used to treat Merkel cell cancer (a rare type of skin cancer) that has spread to other parts of the body. It is also being studied in the treatment of other types of cancer. Avelumab binds to a protein called PD-L1, which is found on some cancer cells. Avelumab may block PD-L1 and help the immune system kill cancer cells. It is a type of monoclonal antibody and a type of immune checkpoint inhibitor. Also called Bavencio.

Source: NCI Dictionary of Cancer Terms

2017-03-27 Date last modified: 2017-05-11Avelumabimmune checkpoint inhibitor