Definition of infigratinib phosphate

infigratinib phosphate

(IN-fig-RA-tih-nib FOS-fayt)
A drug used to treat adults with cholangiocarinoma (bile duct cancer) that is locally advanced and cannot be removed by surgery or has spread to other parts of the body. It is used in patients whose cancer has a FGFR2 gene fusion or other change in the structure of the FGFR2 gene and has already been treated. It is also being studied in the treatment of other types of cancer. Infigratinib phosphate blocks a protein called FGFR, which may help keep cancer cells from growing and may kill them. It may also prevent the growth of new blood vessels that tumors need to grow. Infigratinib phosphate is a type of tyrosine kinase inhibitor and a type of antiangiogenesis agent. Also called Truseltiq.

Source: NCI Dictionary of Cancer Terms