Research

Protocol Office (PRMC/QASMC)

The Protocol Office at the Siteman Cancer Center assists and manages the activities of the two research review committees:

  • Protocol Review and Monitoring Committee (PRMC)
  • Quality Assurance and Safety Monitoring Committee (QASMC)

Office Location

Center for Outpatient Health – 8th Floor

Mailing Address

CB 8100 4901 Forest Park Ave., Suite 800 St. Louis, MO 63108-1401

Protocol Review and Monitoring Committee (PRMC)

Siteman Cancer Center’s Protocol Review and Monitoring Committee (PRMC) reviews all cancer-related clinical research studies involving human subjects in order to ensure that they are scientifically and statistically sound, appropriately designed, feasible for completion based on the SCC’s patient population and existing clinical trials portfolio, and in compliance with NIH guidelines for clinical trials, including monitoring for accrual and undue toxicity.

The PRMC is specifically responsible for:

  • providing scientific peer-review for all cancer research studies conducted under the auspices of the SCC including, but not limited to, institutional, industrial, and national cooperative group studies;
  • ensuring proper study design;
  • reviewing all active trials under its purview for renewal/termination; and
  • reviewing accrual in all active cancer research trials.

Co-chairs: Joel Picus, MD, Julie Margenthaler, MD, Perry Grigsby, MD, Brad Kahl, MD, and Bettina Drake, PhD, MPH

Manager: Stephanie Myles, slmyles@wustl.edu

Protocol Coordinator: Sharon Phillips, MS, CCRC, phillips.sharon@wustl.edu

Protocol Coordinator: Laura Gross, lauragross@wustl.edu

For a complete list of PRMC members, click here.

Protocol Review and Monitoring Committee Policies and Procedures (Updated October 2019; last major update May 2019)

Summary of Operational Changes to PRMC P&P (last major update May 2019)

FY20 Schedule of PRMC Meetings and Deadlines

FY20 Schedule of BSS Meetings and Deadlines

Focus Groups and Leaders

PRMC Submission Forms and Instructions

PRMC Reviewer Forms

Quality Assurance and Safety Monitoring Committee (QASMC) Information

To maintain National Cancer Institute (NCI) designation, the Alvin J. Siteman Cancer Center (SCC) must ensure that research data generated under its sponorship are of high quality, reliable, verifiable and reproducible. The QASMC oversees the data and safety monitoring of institutional trials, reviewing all reportable adverse events that occur on research studies conducted under the auspices of the Siteman Cancer Center, and reviews quality assurance audits conducted annually on institutional therapeutic trials, as well as any other trial, at the request of the PRMC.

Chair: Nancy Bartlett, MD

QA specialist: Catie Knoerle, knoerlec@wustl.edu

QA specialist: Jennifer Edwards, edwardsj@wustl.edu

QA Specialist: Daveta Jenkins, davetaj@wustl.edu

QA Specialist: Sarah Uffman, suffman@wustl.edu

Manager: Stephanie Myles, slmyles@wustl.edu

For a complete list of QASMC members, click here.

Quality Assurance and Safety Monitoring Committee Policies and Procedures (Updated August 2019)

QASMC Forms