PRMC Submission Forms and Instructions

All submissions to the Protocol Review and Monitoring Committee must include the corresponding PRMC form listed below. You may download the forms directly from the website or a copy of the form can be e-mailed to you from the Protocol Office.

The corresponding submission grids detail what documents, in addition to the PRMC form, must be included in the submission, depending on the type of study.

To create a new submission within OnCore please use the Confluence work instructions, which provide step-by-step directions and screenshots.

If you have submitted a study to the IRB that has been flagged for PRMC review in myIRB and/or HRPO staff have indicated that PRMC review is necessary, please note that you will need to make a SEPARATE submission to PRMC through OnCore.  More information on this requirement, how to obtain OnCore access and resources for creating an Initial Review for PRMC may be found here.

Need assistance?

PRMC Open Office Hour (OOH): Connect one-on-one with a Siteman PRMC Staff member Monday – Friday between 2:00 and 3:00PM for help with any questions regarding oncology research submissions. To join the private Zoom meeting room during OOH, please visit:

  • Meeting ID: 995 8771 5178
  • Passcode: 542944
  • Dial by your location:  +1 312 626 6799 US (Chicago)

Change reviews

To be submitted concurrently with all IRB modification submissions (except study team updates and marketing materials).

Continuation reviews

To be submitted concurrently with the annual IRB renewal submission.


Studies are eligible to close with PRMC once the study is permanently closed to accrual and the intervention or data collection has ended.