Treatment

Bone Marrow and Stem Cell Transplant

Siteman’s adult bone marrow and stem cell transplant program is one of the largest in the world, performing nearly 500 transplants each year – and more than 6,000 since 1982. We have performed unrelated donor transplants since 1991.

  • Our bone marrow and stem cell transplant program is accredited by the Foundation for the Accreditation of Cellular Therapy (FACT) for both autologous and allogeneic transplants and the collection of cellular products and processing. We are an active member of the National Marrow Donor Program, International Bone Marrow Transplant Registry, North American Bone Marrow Transplant Registry, Blood and Marrow Transplant Clinical Trials Network and Cancer and Leukemia Group B (CALGB) Transplant Consortium.
  • Unlike many centers, Siteman’s hematologic malignancy and transplant programs are integrated. Our team offers transplantation as part of a full spectrum of treatment options tailored to each patient’s specific needs. In addition to 14 transplant physicians and six medical oncologists, the team includes transplant coordinators, transplant nurse practitioners, dietitians, physical therapists, social workers and others.
  • Dedicated facilities include a 54-bed inpatient unit for patients with hematologic malignancies and an adjacent 31-bed unit for patients undergoing transplant, which offers ten ICU beds and rooms with HEPA filtration systems. Also available are on-site leukapheresis, HLA typing, cytogenetics, cryopreservation and photopheresis for GVHD.
  • At any given time, we offer more than 60 therapeutic clinical trials for patients with leukemia, lymphoma, multiple myeloma and related disorders, including protocols incorporating transplant. In 2013, our physicians enrolled more than 500 patients into these trials. Our large patient population allows us to offer single- institution trials and provides us with access to a wide range of tissue samples for banking and future study.
  • Siteman is the premier center for innovative leukemia research, with a bench-to-bedside approach that has the potential to improve survival and reduce treatment-related side effects. The first cancer genomes to be sequenced in the world were from patients with acute myeloid leukemia (AML) being treated at Siteman, and all of the work was done in collaboration with The Genome Institute at Washington University. The National Cancer Institute has awarded Siteman leukemia researchers their third Program Grant (PPG), the latest totaling $14.3 million, and an $11.3 million Specialized Program of Research Excellence (SPORE) grant.
  • Siteman’s nationally recognized lymphoma team provides care to more than 400 new patients a year, many with relapsed or refractory disease who go on to receive transplants. A number of clinical trials are offered, including those testing new agents as salvage therapy and a Radiation Therapy Oncology Group protocol for central nervous system lymphoma. FDG-PET is employed to aid in staging and treatment selection. Nuclear imaging specialists at Washington University’s Mallinckrodt Institute of Radiology co-wrote guidelines for the use of PET in lymphoma treatment.
  • Washington University is one of 16 members of the Multiple Myeloma Research Consortium, which aims to accelerate the development of novel and combination treatments through collaboration between industry and academia. Multiple phase I and II clinical trials are available to patients with relapsed and refractory disease. Epidemiological research includes a National Cancer Institute-funded study to assess genetic and blood biomarkers and examine risk factors.

Siteman Cancer Center Facts

  • Nearly 500 bone marrow and stem cell transplants each year.
  • Integrated hematologic malignancy and transplant programs.
  • Three dedicated inpatient units.
  • More than 60 active treatment trials.

Referrals

Siteman offers a team of referral specialists who assist providers seeking treatment for their patients. To request an appointment, call 314-747-3046 or 877-251-6485 toll free from 8 a.m. to 4:30 p.m. Monday through Friday. Referrals also can be made online through a secure appointment request service at www.siteman.wustl.edu/refer.aspx.

To expedite the referral process, our referral specialists may ask you to fax records to us at 314-454-8103.

The mailing address is:

Siteman Cancer Center
Mailstop 90-75-563
4901 Forest Park Ave.
Center for Outpatient Health 8th floor St. Louis, MO 63108

If appropriate, a financial specialist is available to answer questions about health insurance and identify resources for expenses related to cancer care.

Our referral specialists also handle requests for hospital-tohospital transfers during regular business hours. Referring physicians will be quickly connected to a specialist physician on staff at Barnes-Jewish Hospital who can authorize a transfer. After-hours requests can be made by calling the hospital’s Doctors’ Access Line at 314-747-3251 or 800-252-3627.