Breast Cancer Research Program (BCRP)

Program Co-Leaders: Jason Weber, PhD, Katherine Weilbaecher, MD, and Cynthia Ma, MD, PhD

Overview:

The long-term goals of the Breast Cancer Research Program (BCRP) are to define the fundamental mechanisms that regulate breast cancer pathology and then use this information to develop personalized strategies for the prevention, diagnosis, and treatment of all stages and subtypes of breast cancer. The BCRP leadership established collaborative working groups in clinical, basic, and population sciences to identify and develop novel implementation strategies for the diagnosis and treatment of breast cancer. These three groups are guided by the hypothesis that advances in basic and population sciences can be leveraged to enhance the clinical impact in successfully treating breast cancer.

Aims:

The BCRP’s translational efforts have been organized around three specific aims.

  1. Discover, identify, and validate novel personalized clinical targets for breast cancer.
  2. Utilize institutional expertise in basic sciences to define the molecular mechanisms that drive breast cancer progression and metastasis in individuals.
  3. Reduce disparities in breast cancer mortality by identifying personalized risk factors and developing targeted prevention and genomic strategies.

Recorded program seminars and events are available at this link on WUSTL Box.