Siteman Investment Program Research Development Awards (SIP RDAs)

The 2025 Cycle 1 Statements of Intent (SOI) Window is Now Closed.
Deadline for Full Proposals from SOI Applicants is Friday, April 11th at 4pm CST via proposalCENTRAL.

RFA and Notable Changes

2025 Cycle 1 SIP RDA Request for Applications (RFA)

Please read the RFA in its entirety before applying!

  • New table of contents for easier navigation
  • New funding category (GIDA) added for CGI-collaborative projects in the field of genome integrity
  • Established Clinical Trial mechanism has been retired
  • For clinical trial submissions, a formal letter of support from Siteman Protocol Development is required to accompany the Statement of Intent submission.
  • Applicants may now submit for COE supplement funding on parent grants for which they are not the PI, provided they have a letter of support from the PI
  • While SCC expects its support of clinical trials to be supplemented by support from other sources, it is no longer required to be detailed at the time of application. However, applicants who have already secured other sources of support are encouraged to submit this information at the time of application.

Available Funding Categories

  • CLINICAL TRIAL CATEGORY
    • New Clinical Trial Mechanism; up to $300,000 over 3 years
    • Brain Tumor Center (BTC) Early Phase 1 Clinical Trial Mechanism; up to $75,000 over 3 years
  • PRE-R01 CATEGORY
    • The Pre-R01 Mechanism; up to $200,000 over 2 years (includes projects with Prevention and Control focus)
    • Pre-R01 Mechanism for University of Missouri-Columbia Collaboration; up to $200,000 over 2 years
  • TEAM SCIENCE CATEGORY
    • Team Science Mechanism; up to $800,000 over 2 years
  • NEW: GENOME INTEGRITY DEVELOPMENT AWARDS (GIDA) CATEGORY
    • GIDA Mechanism; up to $100,000 over 2 years
  • COE SUPPLEMENT CATEGORY
    • COE Supplement Mechanism; up to $50,000 over 1 year (may request up to $100,000 directs with pre-approval as outlined in the RFA)

Complete information on each mechanism can be found in the Request for Applications (RFA) each cycle.

2025 Cycle 1 Official Dates

Announcement: February 4, 2025
Statement of Intent (REQUIRED) deadline: March 7, 2025 at 4pm CST
Application deadline: April 11, 2025 at 4pm CST
Anticipated decision notice: June 2025
Start date: July 1, 2025

2025 Cycle 1 Application Documents

SIP RDA Request for Applications (RFA) – New table of contents
SIP RDA Application Cover Sheet Form – (required – updated 02/2025) – for all non-GIDA applications.
SIP RDA GIDA Application Cover Sheet Form – (required – updated 02/2025
SIP RDA Clinical Trial Category Budget Form – (required – updated 02/2025)

General SIP RDA Cycle Timelines

GENERAL SIP DATE GUIDELINES* Cycle 1 2025
Current Cycle
 Cycle 2 2025
Next Cycle
Announcement: February 4, 2025
 July 2025
Statement of Intent deadline:
REQUIRED
 March 7, 2025
 August 2025
Full Application Deadline:
via proposalCENTRAL		 April 11, 2025
 September 2025
Anticipated decision notices: June 2025
 December 2025
Start dates: July 1, 2025
 January 1, 2026
*Dates may vary based on weekends, holidays, and other unforeseen circumstances.

Please consult the specific cycle’s RFA announcement for official deadlines.

Success Rates

Success rates have been computed over the span of SIP RDA by mechanism and include applications that were scientifically reviewed. Success rates are determined by dividing the number of applications funded by the total number of applications reviewed. The current success rate for the Pre-R01 Category is 19%.

Re-submissions are welcome and encouraged every cycle. The success rate for re-submissions across all mechanisms is 30%.

Previous Awardees

For the full list of previous SIP RDA awardees, click HERE.

Contact

Contact Steve Baer at Siteman Cancer Center for more information or any questions, [email protected].