News and Events

Congratulations to Drs. Abby Green and Alice Meroni for delivering two outstanding talks at the Arturo Falaschi Conference on DNA replication and genome stability in Trieste, Italy: https://www.icgeb.org/dna-replication-and-genome-maintenance-2022/

Congratulations to Abby Green for her new story on the mutagenic effects of endogenous deaminases!
- Rachel A DeWeerd, Eszter Németh, Ádám Póti, Nataliya Petryk, Chun-Long Chen, Olivier Hyrien, Dávid Szüts, Abby M Green. Prospectively defined patterns of APOBEC3A mutagenesis are prevalent in human cancers. Cell Rep. 2022 Mar 22;38(12):110555. doi: 10.1016/j.celrep.2022.110555. PMID: 35320711 DOI: 10.1016.
Congratulations to our newest CGI member Priyanka Verma for receiving the 2022 Rivkin Pilot Study Award! Many more to come!

Congratulations to the Mosammaparast lab for the recent paper in collaboration with the Reynoird, Vindigni, He, and Tainer labs on the mechanism of RNA methylation!
- Tsao N, Brickner JR, Rodell R, Ganguly A, Wood M, Oyeniran C, Ahmad T, Sun H, Bacolla A, Zhang L, Lukinović V, Soll JM, Townley BA, Casanova AG, Tainer JA, He C, Vindigni A, Reynoird N, Mosammaparast N. Aberrant RNA methylation triggers recruitment of an alkylation repair complex. Mol Cell. 2021 Oct 21;81(20):4228-4242.e8. doi: 10.1016/j.molcel.2021.09.024. PMID: 34686315.

Congratulations to the Vindigni lab for the recent paper in collaboration with Zou lab on the mechanisms of ssDNA gap repair!
- Tirman S, Quinet A, Wood M, Meroni A, Cybulla E, Jackson J, Pegoraro S, Simoneau A, Zou L, Vindigni A. Temporally distinct post-replicative repair mechanisms fill PRIMPOL-dependent ssDNA gaps in human cells. Mol Cell. 2021 Oct 7;81(19):4026-4040.e8. doi: 10.1016/j.molcel.2021.09.013.PMID: 34624216.

Congratulations to Abby Green for her recent paper in collaboration with the Weitzman lab and the Garcia lab on the APOBEC3A deaminase in Embo Rep!
- Green AM, DeWeerd RA, O’Leary DR, Hansen AR, Hayer KE, Kulej K, Dineen AS, Szeto JH, Garcia BA, Weitzman MD.. Interaction with the CCT chaperonin complex limits APOBEC3A cytidine deaminase cytotoxicity EMBO Rep (2021): e52145. doi:10.15252/embr.202052145. PMID:34347354.

Congratulations to David O’Leary and Silvia Pegoraro for winning our competition for the best images for the CGI website!

Welcome to Dr. Priyanka Verma as a new member of the Center for Genome Integrity! Priyanka has been recruited from the Department of Cancer Biology at the University of Pennsylvania and will focus on critical vulnerabilities of cancer cells and their response to genotoxic stresses. She will start in August, 2021 and she will be the first Siteman Cancer Center Pedal the Cause Investigator!