Core 1: Biostatistics and Bioinformatics Core

Core Director: Esther Lu, PhD

The Biostatistics and Bioinformatics Core provides state-of-the-art statistical support for all Route 66 Endometrial Cancer SPORE investigators and projects. The Core will provide statistical support on all aspects of study design, study execution and monitoring, database development and quality control, and data analysis and interpretation. Biostatistics and Bioinformatics Core members have diverse expertise, and established long-term collaborations with SPORE members at Washington University, University of Oklahoma Health Sciences Center, and University of New Mexico. Their statistical expertise will support newly developing research themes of the SPORE projects, such as Bayesian adaptive trial design, immunotherapy and target therapy trial design, biomarker-guided personalized medicine study, next-generation sequencing, and high-throughput omics data analysis, monitoring minority accrual, OnCore, REDCap, and data management and analysis for clinical studies.

In Aim 1, the Core will provide biostatistics and bioinformatics collaborations for SPORE projects and Developmental Research Program studies.

In Aim 2, the Core will provide biostatistics and bioinformatics support and training to early-career investigators through the Career Enhancement Program.

In achieving its aims, the Biostatistics and Bioinformatics Core will ensure that robust statistical methods and reproducible omics analyses are available to support all Route 66 Endometrial Cancer SPORE investigators.

Resources related to the Biostatistics and Bioinformatics Core:

Siteman Biostatistics and Qualitative Research Shared Resource

OUHSC Biostatistics & Research Design Shared Resource

UNM Biostatistics Shared Resource

Spore Biostatsandbioinformatics