The Siteman Approach to Lymphoma

Lymphoma is a form of blood cancer that develops from lymphocytes, which are a type of white blood cell. Lymphocytes travel through the blood and lymphatic system to defend the body against foreign invaders such as bacteria and viruses.

Lymphomas usually develop when a change occurs within a lymphocyte, causing the abnormal cell to replicate faster than, or live longer than, a normal lymphocyte. The cancerous lymphocytes can travel through the blood and lymphatic system like normal lymphocytes and spread and grow in many parts of the body, including the lymph nodes, spleen, bone marrow, and other organs.

There are over 90 different types of lymphoma. Some lymphomas are aggressive, while others are slow-growing.

Fortunately, there are many forms of treatment for lymphomas, and some types of lymphoma can be cured. Today, established methods such as chemotherapy and stem cell transplants, as well as exciting new treatments such as CAR T-cell therapy, can bring many lymphoma patients the hope of an extended remission or cure.

At Siteman Cancer Center, our Washington University oncologists are driving the latest innovations in lymphoma treatment – innovations that can help you.

The Siteman Difference

Siteman Cancer Center is the only National Cancer Institute-designated Comprehensive Cancer Center in Missouri. U.S. News & World Report consistently ranks us among the top cancer facilities in the nation.

Since its founding in 1999, Siteman has been leading the charge against cancer from the middle of the Midwest. Our Washington University oncologists and scientists have an impressive track record of discoveries that have fundamentally changed cancer care.

At Siteman, we unite compassionate patient care and ground-breaking cancer research. We treat our lymphoma patients with the newest approaches science has to offer, many of which were studied in laboratories right here at Siteman.

Specialized oncologists

When you come to Siteman, you’ll be treated by oncologists who specialize in the treatment of patients with lymphoma. They also conduct laboratory research into lymphoma and run clinical trials examining new drugs and techniques.

It’s important for lymphoma patients to be treated by specialists because lymphoma is such a complex disease. With countless different types and subtypes, it can be difficult to identify correctly. Successful treatment hinges on having an accurate diagnosis. The lymphoma team at Siteman will ensure that you get the right diagnosis and the right treatment plan.

Meet our lymphoma team.

Safer stem cell transplants

A stem cell transplant (also known as a bone marrow transplant) is sometimes the best option to treat lymphoma. The transplant program at Siteman is one of the largest in the world, and we excel at bringing patients through the procedure safely and successfully.

Learn more about stem cell transplants at Siteman

CAR T-cell Therapy

CAR T-cell therapy is a new treatment that transforms cells from a patient’s own immune system into powerful tools against cancer. It was approved by the FDA in 2017 as a treatment for certain types of lymphoma. Some patients who undergo CAR T-cell therapy have seen long-term remissions.

Siteman was one of the first cancer centers in the nation licensed to perform CAR T-cell therapy and helped conduct the earliest trials of these therapies in lymphoma patients, which means that our physicians are some of the most experienced providers you can find. What’s more, CAR T-cell therapy and similar forms of treatment are an active area of research for Siteman’s Washington University oncologists and scientists. Ongoing clinical trials at Siteman are working to apply CAR T and similar cellular therapies to additional types of cancer.

Read about why Siteman excels at CAR T-cell therapy

Clinical trials

Clinical trials allow patients to access advanced new treatments that have not yet been licensed by the FDA. Sometimes, a clinical trial is the only way to help patients who have not found success with other forms of treatment.

Siteman offers more clinical trials than any other facility in the region. If a clinical trial could be a good fit for you, your physicians will be able to include it in your treatment plan.

Review Siteman’s clinical trials for lymphoma patients