SNO 2025 Presentations

Friday, Nov. 21

Session: Telomere Biology in Gliomas
10:15-11:15 a.m. | Kalakaua Ballroom B
CO-ORGANIZER and MODERATOR: Milan G. Chheda, MD
*This session will have CME.

Presentation: TMIC-21 – Dual blockade of Siglec-15 and PD-1, combined with oncolytic Zika virus therapy, confers protection against immune-resistant gliomas.
10:59-11:04 a.m. | Lili’u Theater 310
PRESENTER: Ashwani Kesarwani, M.Sc. (X: @ashwani_kesar)

Oral and Poster Presentations: IMMU-34 – T cell receptor repertoire analysis of mouse glioma infiltrating CD4+ T cells reveals patterns of clonal T effector and T regulatory responses that may influence response to therapy
Poster Presentation: 11:30 a.m.-12:30 p.m. | Kamehameha Exhibit Hall II & III
Oral Presentation: 11:48-11:51 a.m. | Kamehameha Exhibit Hall II & III
PRESENTER: Emilie Russler-Germain, MD, PhD

Poster Presentation: DDDR-59 – Focal Adhesion Kinase (FAK) Inhibitor Synergizes with RAF/MEK inhibitor in Malignant Peripheral Nerve Sheath Tumors with Chromosome 8 Gain
11:30 a.m.-12:45 p.m. | Kamehameha Exhibit Hall II & III
PRESENTER: Dana Borcherding, PhD

Poster Presentation: CNSC-45 – Daily locomotor activity declines with tumor growth and precedes clinical detection of progression in glioblastoma
11:30 a.m.-12:45 p.m. | Kamehameha Exhibit Hall II & III
PRESENTER: Sofia Salvatore-Lannes

Poster Presentation: CTIM-33 – Personalized multivalent DNA vaccination safely induces broad neoantigen-specific T cell responses in newly diagnosed MGMT unmethylated glioblastoma in a clinically relevant time scale
11:30 a.m.-12:45 p.m. | Kamehameha Exhibit Hall II & III
PRESENTER: Ryan Gimple, MD, PhD (X: @ryan_gimple)

Saturday, Nov. 22

Session: The Evolving Landscape of Pediatric Low-Grade Glioma—From Bench to Bedside
10:35-11:35 a.m. | Kalakaua Ballroom B
CO-ORGANIZER and MODERATOR: Mohamed Abdelbaki, MD (X: @MoAbdelbaki)
*This session will have CME.

Presentation: CTIM-11 – Laser interstitial thermal therapy plus pembrolizumab prolongs survival and elicits robust anti-tumor immunity in recurrent, refractory high-grade astrocytoma: a Phase 1/randomized Phase 2b trial
10:35-10:42 a.m. | Lili’u Theater 310
WashU Medicine research presented by collaborator David Tran, MD, PhD, University of Southern California
*Abstract Award presented by The Sontag Foundation

Poster Presentation: CTIM-04 – A phase II study of azeliragon in combination with radiation therapy in newly diagnosed patients with MGMT-unmethylated glioblastoma
11:45 a.m.-1:05 p.m. | Kamehameha Exhibit Hall II & III
PRESENTER: Jiayi Huang, MD

Poster Presentation: CTIM-33 – Personalized multivalent DNA vaccination safely induces broad neoantigen-specific T cell responses in newly diagnosed MGMT unmethylated glioblastoma in a clinically relevant time scale
11:45 a.m.-1:05 p.m. | Kamehameha Exhibit Hall II & III
PRESENTER: David Giles, MD, PhD

Presentation: CTIM-33 – Personalized multivalent DNA vaccination safely induces broad neoantigen-specific T cell responses in newly diagnosed MGMT unmethylated glioblastoma in a clinically relevant time scale
12:24-12:27 p.m. | Kamehameha Exhibit Hall II & III
PRESENTER: Ryan Gimple, MD, PhD (X: @ryan_gimple)

Session: Neuro-Oncologic Health Disparities Around the World
3:15-4:15 p.m. | Kalakaua Ballroom C
CO-ORGANIZER, SPEAKER and PANELIST: Mohamed Abdelbaki, MD (X: @MoAbdelbaki)

Sunday, Nov. 23

Session: Neurogenetic Tumor Syndromes Abstract Session
9:45-10:45 a.m. | O’ahu 313 ABC
MODERATOR: Nicole Brossier, MD, PhD

Presentation: DDDR-59 – Focal Adhesion Kinase (FAK) Inhibitor Synergizes with RAF/MEK inhibitor in Malignant Peripheral Nerve Sheath Tumors with Chromosome 8 Gain
10:24 a.m.-10:29 a.m. | O’ahu 313 ABC
PRESENTER: Dana Borcherding, PhD

Session: Synergies and Conflict in Surgery and Precision Medicine
11 a.m.-noon | Kalakaua Ballroom A
CO-ORGANIZER and MODERATOR: Albert H. Kim (X: @AlbertHKimMDPhD)
*This session will have CME.

Session: Extrachromosomal DNA and Cancer Pathogenesis
11 a.m.-noon | Kalakaua Ballroom B
CO-ORGANIZER and MODERATOR: Milan G. Chheda, MD
*This session will have CME.