ASH 2025 Presentations

Friday, Dec. 5

Friday Satellite Symposia
Session: Expert Second Opinion: Investigators Discuss the Optimal Management of Patients with Myelofibrosis and Systemic Mastocytosis
3-6 p.m. EST | Hyatt – Regency TUV
SPEAKER: Stephen Oh, MD, PhD (X: @mpndoc)
*This session will have CME.

Scientific Workshop: Response Prediction and Clonal Evolution
Presentation: AML Mutation Clearance after Induction: an Integrated Genomic Approach to Define Subclonal Responses to Therapy
4:50-5:55 p.m. EST | Room OCCC – W308
SPEAKER and PANELIST: Timothy Ley, MD

Friday Satellite Symposia
Session: Expert Second Opinion: Investigators Discuss the Role of Novel Treatment Approaches in the Care of Patients with Follicular Lymphoma and Diffuse Large B-Cell Lymphoma
7-10 p.m. EST | Hyatt – Regency TUV
SPEAKER: Nancy Bartlett, MD (X: @NancyBartlettMD)
*This session will have CME.

Saturday, Dec. 6

Trainee Activities and Services: Career Development Lunch
Presentation: Hematology-Focused Fellowship Training Program
11:15 a.m.-12:15 p.m. EST | Hyatt – Windermere Ballroom
SPEAKER: Amy Zhou, MD

Scientific Symposia: Discovering the Biology of Hematopoiesis Through Studies of Bone Marrow Failure Syndromes
Presentation: The Connections Between Telomere Biology and Hematopoiesis
2:20-2:40 p.m. EST | Hyatt – Plaza Int’l HIJK
SPEAKER: Luis Batista, PhD

Oral Abstract Session: 501. Hematopoietic Stem and Progenitor Cells and Hematopoiesis: Basic and Translational: Chromatin and transcriptional regulation in hematopoietic lineage commitment
Presentation: MLL3 and MLL4 maintain hematopoietic stem cell multipotency by actively opposing a B-cell default state
2:45-3:00 p.m. EST | OCCC – W311EFGH
SPEAKER: Helen Wang

Oral Abstract Session: 323. Disorders of Coagulation, Bleeding, or Fibrinolysis, Excluding Congenital Hemophilias: Clinical and Epidemiological: Novel Insights into Diagnostics and Therapeutics of Bleeding in Inherited, Acquired Coagulopathies and BDUC
Presentation: Long-term safety and effectiveness of systemic bevacizumab for chronic severe bleeding in idiopathic gastrointestinal angiodysplasia, esophageal varices, and angiodysplasia of von willebrand disease and acquired von willebrand syndrome
4-4:15 p.m. EST | OCCC – W304EFGH
SPEAKER: Nardeen Ayad, MD

Poster Abstract Session: 624. Hodgkin Lymphomas: Clinical and Epidemiological: Poster I
Presentation: Interim and end-of-treatment FDG-PET demonstrate limited ability to predict 3-year progression-free survival with nivolumab-AVD in first-line treatment of advanced stage Hodgkin lymphoma: Imaging sub-analysis of Phase 3 S1826 study (Presentation ID 1851)
5:30-7:30 p.m. EST | OCCC – West Halls B3-B4
PRESENTER: Nancy Bartlett, MD (X: @NancyBartlettMD)

Poster Abstract Session: 634. Myeloproliferative Syndromes: Clinical and Epidemiological: Poster I
Presentation: Dual transfusion independence and spleen volume reduction is associated with overall survival in patients with myelofibrosis treated with momelotinib: Post hoc analyses of SIMPLIFY-1 and MOMENTUM (Presentation ID 2023)
5:30-7:30 p.m. EST | OCCC – West Halls B3-B4
PRESENTER: Stephen Oh, MD, PhD (X: @mpndoc)

Poster Abstract Session: 634. Myeloproliferative Syndromes: Clinical and Epidemiological: Poster I
Presentation: Transfusion independence with momelotinib regardless of baseline erythropoietin levels in the Phase 3 SIMPLIFY-1 trial (Presentation ID 2025)
5:30-7:30 p.m. EST | OCCC – West Halls B3-B4
PRESENTER: Stephen Oh, MD, PhD (X: @mpndoc)

Poster Abstract Session: 332. Thrombosis and Anticoagulation: Clinical and Epidemiological: Poster I
Presentation: Distribution and risk for bleeding in patients with cancer by anticoagulant therapy exposure (Presentation ID 1362)
5:30-7:30 p.m. EST | OCCC – West Halls B3-B4
PRESENTER: Kristen Sanfilippo, MD, MPHS (X: @KSanfilippoMD)

Poster Abstract Session: 301. Platelets and Megakaryocytes: Basic and Translational: Poster I
Presentation: Tumor necrosis factor-alpha (TNFα) drives pathologic platelet hyperreactivity through signaling on hematopoietic stem/progenitor cells and expansion of canonical megakaryocytic progenitors. (Presentation ID 1250)
5:30-7:30 p.m. EST | OCCC – West Halls B3-B4
PRESENTER: Joshua Siner, MD

Special-Interest Session: Hematology Inclusion Pathway (HIP) Oral Presentations – Health Services Outcomes
Presentation: Analysis of the North American Transplant Outcomes (NAMTO) Study
6:30-8 p.m. EST | Hyatt – Plaza Int’l F
SPEAKER: Helen Ajufo, MD, MS

Sunday, Dec. 7

Special-Interest Session: Medical Educators’ Symposium
Presentation: Breakout 4: Innovation in Education for the Current Generation – Facilitator A
8:42-8:49 a.m. EST | Hyatt – Plaza Int’l DEFG
SPEAKER: Sana Saif Ur Rehman, MD

Scientific Program: Joint Session: Game of Clones – The Evolution of Hematopoiesis from Birth to Aging
Presentation: Genetic-Epigenetic Regulators Providing a Competitive Advantage to HSCs
9:50-10:10 a.m. EST | OCCC – W312
SPEAKER: Grant Challen, PhD (X: @ChallenLab)

Marquee Session: Announcement of Awards: ASH Mentor Award
1:30-2 p.m. EST | OCCC – West Hall D2
AWARDEE: Jorge Di Paola, MD

Poster Abstract Session: 631. Myeloproliferative Syndromes and Chronic Myeloid Leukemia: Basic and Translational: Poster II
Presentation: Longitudinal genomic shifts associated with disease transformation in patients with polycythemia vera (PV) enrolled in REVEAL (Presentation ID 3749)
6-8 p.m. EST | OCCC – West Halls B3-B4
PRESENTER: Stephen Oh, MD, PhD (X: @mpndoc)

Poster Abstract Session: 616. Acute Myeloid Leukemias: Investigational Drug and Cellular Therapies: Poster II
Presentation: A randomized study of conventional chemotherapy +/- uproleselan in older adults with Acute Myeloid Leukemia eceiving intensive induction chemotherapy (Alliance A041701) (Presentation ID 3415)
6-8 p.m. EST | OCCC – West Halls B3-B4
PRESENTER: Geoffrey Uy, MD

Monday, Dec. 8

Scientific Symposia: Special Symposium on the Basic Science in Hemostasis and Thrombosis
Presentation: Long-term safety and effectiveness of systemic bevacizumab for chronic severe bleeding in idiopathic gastrointestinal angiodysplasia, esophageal varices, and angiodysplasia of von willebrand disease and acquired von willebrand syndrome
5:30-5:45 p.m. EST | OCCC – Valencia Room W415D
SPEAKER: Nardeen Ayad, MD

Poster Abstract Session: 631. Myeloproliferative Syndromes and Chronic Myeloid Leukemia: Basic and Translational: Poster III
Presentation: Activating STIM1 mutations drive the development of myelofibrosis (Presentation ID 5528)
6-8 p.m. EST | OCCC – West Halls B3-B4
PRESENTER: Molly Brakhane (X: @MBrakhane)

Poster Abstract Session: 711. Cell Collection and Manufacturing of HSPCs, CAR-T Cells, and Other Cellular Therapy Products: Poster III
Presentation: Preclinical feasibility analysis for Phase I study using adoptive iNKT cell transfer to prevent GVHD (Presentation ID 5967)
6-8 p.m. EST | OCCC – West Halls B3-B4
PRESENTER: Kelsey Busken, MD, MSc

Poster Abstract Session: 501. Hematopoietic Stem and Progenitor Cells and Hematopoiesis: Basic and Translational: Poster III
Presentation: Critical role for MLL3-phd domains in HSC self-renewal and AML suppression (Presentation ID 4928)
6-8 p.m. EST | OCCC – West Halls B3-B4
PRESENTER: Rohini Muthukumar, PhD

Poster Abstract Session: 613. Acute Lymphoblastic Leukemias: Therapies Excluding Allogeneic Transplantation: Poster III
Presentation: Integrating next-generation sequencing disease evaluation and PCR based CAR-T cell tracking to guide decision making in a real-world cohort of pediatric B-cell ALL patients (Presentation ID 5123)
6-8 p.m. EST | OCCC – West Halls B3-B4
PRESENTER: Thomas Pfeiffer, MD

Poster Abstract Session: 602. Myeloid Oncogenesis: Basic: Poster III
Presentation: NUP98-rearranged pediatric AML is sustained by a conserved leukemia stem cell program with SPNS2/3 as a targetable vulnerability (Presentation ID 5002)
6-8 p.m. EST | OCCC – West Halls B3-B4
PRESENTER: Jihye Yoon

Tuesday, Dec. 9

Marquee Session: Presidential Symposium
Presentation: Novel Therapeutic Approaches
10:45-11:15 a.m. EST | OCCC – West Hall D2
SPEAKER: John DiPersio, MD, PhD